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This research explains the impact of informal institutions (corruption control) and formal institutions (number of procedures, education and entrepreneurship training and skills, access to credit and technology absorption) on entrepreneurship development in 10 in selected Middle East and North Africa (MENA) countries, including Iran during 2005 – 2019. The type of study is descriptive. The present article estimates a panel data model by using the available data from international statistical institutes. Eviews and Stata14 software’s are used for the calculations. The results show that the if corruption control increases, the entrepreneurship will increase, since there is a positive and significant relationship between corruption control and formal institutions, and entrepreneurship development. Among the MENA countries, corruption control has the least impact on entrepreneurship in Iran and the highest impact in Qatar. Also, corruption control, training and skills and technology absorption have had great impacts on the entrepreneurship development.