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Giles, Goat-Boy is a black comedy to bite everyone. Embodied in a postmodern fabulation, Barth’s sense of humor allows him to create a political allegory on any structure of power that claims to save humanity. GILES, a hybrid of a machine and a goat, is tasked with the mission to lead the so-called academic society through instrumental intellect. But he can only go so far as not to create a conflict of interest between the ruling powers. The pattern used in creating Giles is an imitation of the classic patterns in creation and journey of a hero, except that Giles is destined to appear as a scapegoat against the positivist Sphinx of Time. Such an approach begs the main question of the research: How ideological systems sacrifice their heroes to secure their interests? This hypothesis is also in line with Frankfurt School’s critical theory, which considers the capitalist system to be a violation of freedom and social values. The intellectuals such as Horkheimer and Adorno consider man to be a victim of objectification and alienation arising from social and political conflicts. They also believe that hegemonic systems have humiliated man with false pleasures. Just as Giles fails to reform the most powerful ruling system, WESCAC, so Barth symbolically paints a bleak picture of human destiny in modern society today. The purpose of the research is to raise human awareness about the harsh laws that are the ominous products of instrumental intellect, as one of the defining elements of capitalist system.
 

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Tense plays an important and determining role in human verbal communication; therefore, one of the things that should be addressed in language teaching is the discussion of time and ways to recognize it. Considering the role and importance of grammatical tense recognition in language learning and the lack of related research regarding Persian language learning, the purpose of the present research is to investigate the role of available cues in sentences to recognize grammatical tense by Chinese Persian learners of beginner and advanced levels; For this purpose, 49 Persian learners of Chinese language were selected by available sampling method and divided into two groups of Chinese language beginner (26) and advanced (23) based on the level determination test. The instruments used in this research were two tests in two stages; In the first stage, by using the sentence recognition test, the subjects marked the time of the sentences they heard in the answer sheet, and in the second stage, the same test was performed; with the difference that in this test, the sentences did not have time adverbs. The results of this research showed that the subjects of the beginner Chinese language meaningfully used lexical clues when recognizing the time of the sentence, and the subjects of the advanced level simultaneously used two lexical clues and present tense. Regarding the role of gender, the results showed that there is no significant relationship between gender and the ability to understand sentence time. The results of this research can be useful for language learners, teachers, and producers of educational content and also for test designers.
 

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The gill Structure and localization of Na⁺, K⁺-ATPase were examined through branchial arches of the Persian sturgeon, Acipenser persicus larvae (25 days-post-hatched, 417.3 mg). Studies were conducted through light microscopy (H&E Staining) and immunofluorescence for Na⁺, K⁺-ATPase. Results showed each gill consisted of four complete holobranches and opercular hemibranch. Each filament carried rows of lamellae consisting of a network of interconnecting blood lacunae, which were lined by pillar cell flanges. Pavement cells covered the outermost layer of the lamella and blood cells were found in lacunae. High density of ionocytes (529.73 per mm² of the gill tissue) was found at the base of the lamella, in the interlamellar regions, on the filaments and the septums. Ionocytes possessed large size and round basal nuclei. Ionocytes possessed strong immunofleurescence in their cytoplasm, especially in the basolateral sides because of high concentration of the enzyme. The results showed that the main structures of the gill has already been formed at this developmental stage of the Persian sturgeon, and along with its respiratory and excretory roles, it also plays an important role in osmoregulation.

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The purpose of this study was to determine the distribution of Tobacco streak virus (TSV) in the vegetable fields of the Markazi, Qom, Lorestan and Hamadan provinces. This study was performed in 2017, and a total of 475 samples of parsley plants were collected. Using the specific antibody of the virus, the TSV infection of these samples was investigated by the immunosorbent assay through the double antibody sandwich ELISA (DAS-ELISA) method. The results of this study indicated that the TSV infection of parsley samples in Qom, Markazi, Hamedan and Lorestan provinces were 14, 18.8, 15.4 and 20.1%, respectively. Also, the phylogenetic analysis of nucleotide and amino acid sequences of the coat protein of these isolates showed that Iranian and Indian isolates could be clustered along with each other. The phylogenetic tree obtained based on nucleotide and amino acid sequences of the coat protein gene, showed that the isolates were divided into two and three clusters, respectively. Iranian isolates were clustered along with global TSV isolates and other Ilarviruses formed a separate cluster. This is the first report of TSV genetic diversity in Iran, and also the first report of TSV infection in the vegetable fields of Qom, Markazi, Hamedan and Lorestan provinces.

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Aims: Antimicrobial peptides (AMPs) are beneficial compounds that could be used as a new and effective method to suppress microbes. Both Ib-AMP4 and LL37 are antimicrobial peptides with a wide range of antimicrobial activities. This research aimed to evaluate the antibacterial potential of LL37-rIb-AMP4 hybrid protein as an antimicrobial agent against pathogenic bacteria. Therefore, its antibacterial effects against Acinetobacter baumannii, Pseudomonas aeruginosa, vancomycin-resistant Enterococcus (VRE), and methicillin-resistant Staphylococcus aureus (MRSA) were investigated in vivo and in vitro.

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Cucumber mosaic virus (CMV) is one of the most important viruses that globally cause disease outbreaks in horticultural, vegetable, and agronomic crops. To investigate the incidence of viruses infecting Achillea species (yarrows), 350 samples with mosaic, yellowing, and deformation symptoms were collected from different Markazi province locations during the spring seasons of 2017, 2018. CMV infection was detected by using DAS-ELISA. Five samples were selected for phylogenetic studies based on sampling areas and yarrow’s species. A 657 bp fragment of coat protein was amplified using specific primers of CMVCPr and CMVCPf in RT-PCR, cloned and sequenced. Obtained sequences of this study were compared with the retrieved sequences from GenBank. The identities of the CP at the nucleotide and amino acid levels were 95% and 100%, respectively, and are close to other Iranian isolates of CMV. Constructed phylogenetic tree showed that five Iranian isolates from yarrows were placed in the subgroup IB. This finding is the first genetic analysis of CMV from yarrow in Iran.

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Background: Shigella and Enterohemorrhagic Escherichia coli are among the most common causes of bacterial diarrhea, and no effective vaccine candidate for these bacteria have approved yet. Due to the role of IpaD protein and Shigella enterotoxin B subunit (StxB) in Shigella and E. coli O157: H7 pathogenicity, STX1B-IpaD chimeric protein can be used as a suitable molecule to produce a recombinant vaccine candidate. This study aimed to clone, express, and purify STX1B-IpaD chimeric protein to develop an effective vaccine candidate against Shigella and E. coli O157: H7 species. Materials and Methods: IpaD gene with NdeI and BamHI restriction enzyme sites was isolated from a recombinant vector and subcloned into the pET28a -STX1B expression vector. Vector was transferred to E.coli strain Rosetta (DE3) and confirmed by PCR and restriction enzyme digestion. SDS-PAGE and western blotting were used to confirm the recombinant protein. The recombinant STX1B-IpaD protein was purified by affinity chromatography, and its concentration was measured by the Bradford method. Results: The PCR and restriction enzyme digestion showed the accuracy of the gene cloning. The protein electrophoresis showed the proper expression and correct molecular weight (27 kDa) of STX1B-IpaD. The western blot analysis confirmed the recombinant protein. The recombinant protein concentration was estimated at more than 0.3 gr/L. Conclusion: An effective method for the production of recombinant proteins is codon optimization and effective expression in heterologous hosts. After the immunogenicity in the animal model, this recombinant protein can be used as a chimeric vaccine candidate against EHEC and Shigella bacteria.

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Chaotic dynamics of spin-orbit motion of a triaxial gyrostat satellite under the gravity gradient perturbations is considered. The Hamiltonian approach is used for modeling of the coupled spin-orbit equations of motion. The complex Hamiltonian of the system is reduced via the extended Deprit canonical transformation. This reduction yields to the derivation of the perturbation form of the Hamiltonian which can be used in the Ricci curvature criterion based on the Riemannian manifold geometry for the analysis of chaos. The results obtained from Ricci method as well as the values from the Lyapunov exponent demonstrate the presence of a strange attractor and chaos phenomenon in the perturbed system. The simulation results based on the numerical methods such as Poincare' section, trajectories of phase portrait, and time series responses confirm the heteroclinic bifurcation and chaos in the system.

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In this work, governing equations of the feed line, cut-off valve, and the starter system are analyzed mathematically and numerically. In the mathematical solution, the stability of the valve system is considered using the Laplace transform along with the linearization of the equations of the system. According to parameter design of the feed pipe–valve system, the system demonstrates the stable behavior in the effective parameter of the valve system on the basis of the Nyquist and Bode stability criterion. In the numerical solution, the steady state behavior of the cut-off valve is simulated during the cut-command. Then the rate of the pressure variation, mass flow rate through of the valve, gas pressure of the starter system, and the upstream pressure of the valve (water hammer) are considered based on the valve's poppet motion. The comparison of the simulation results with the experimental data depicts only 13 percent error in the mass flow rate through of the valve. In the last time of the closing valve, there is no variation in the mass flow rate in the valve due to the excessive loss factor of the valve when the valve approximately is closed. The results show that the closure of the cutoff valve shall be provided in accordance with allowable maximum pressure of the hydraulic shock on the established

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Sociocultural Theory (SCT) of second language learning puts the emphasis on social interaction and regards it as a pre-requisite for cognitive development (Vygotsky, 1978). Drawing on the SCT, the present study aimed to delve into the possible effect of ZPD-based teacher and peer feedback on reading comprehension and reading strategy use of EFL learners. In so doing, 75 Iranian EFL learners, who were randomly assigned into two experimental and one comparison groups, participated in a quasi-experimental study. The data were collected through Oxford Placement Test (OPT), reading comprehension test and reading strategy questionnaire. One of the experimental groups received teacher feedback based on Aljaafreh and Lantolf's (1994) regulatory scale while the other experimental group accomplished the reading task using the feedback provided by the peers. Results obtained from the one–way ANOVA and Tukey test demonstrated that both experimental groups, teacher and peer, gained significantly more and performed better than the comparison group in reading comprehension while there was no significant difference between teacher and peer feedback groups in reading comprehension. The findings of the strategy questionnaire indicated no statistically significant difference between experimental and control groups, leading to the conclusion that students’ grouping did not influence their use of reading strategy. Therefore, it is concluded that peer feedback can be as effective as teacher feedback, aiding teachers to have a learner–centered classroom by implementing peer feedback rather than teacher feedback.

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Apple Stem Pitting Virus (ASPV) is one of the most common viruses of apple and pear trees. During 2012 to 2013, a total of 1053 symptomatic and asymptomatic leaf samples were collected from orchards in nine provinces of Iran. ASPV infection was detected by DAS-ELISA and PCR in 54 samples (5.12%) from seven provinces. Based on the geographical origin, 22 representative isolates were selected for phylogenetic analysis. Twenty-two amplicons with a size of about 370 base pair (bp) comprising partial sequence of the Coat Protein (CP) coding regions of the viral genome were sequenced. Sequence data analysis, showed that the identities of 3'-terminal region of CP gene at both nucleotide and amino acid levels among the Iranian isolates were 95–100% and these isolates were closer to the Asian ASPV isolates than to the other isolates. Constructed phylogenetic tree by Neighbor-joining on the basis of the 3'-terminal region of CP gene sequences showed that the Iranian isolates were categorized into two major groups. Furthermore, phylogenetic and population genetic analysis were carried out on the basis of 3'-terminal region of CP gene which revealed that ASPV isolates were not geographically resolved. Also, all values in the GABranch analysis showed a ratio of substitution rates at Non-synonymous and Synonymous sites (dN/dS) below one, suggesting strong negative selection forces during C-terminal region of the ASPV CP gene history. To the best of our knowledge, this is the first report of distribution and partial genome sequence analysis of the ASPV in Iran.

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Fiber strands due to their flexibility, high aspect ratio, cross-section varieties and degree of crystallinity are adequately strong to be used as reinforcement in composites such as concrete. Newly introduced fiber reinforced concretes (FRC) are the cementitious materials that exhibit reinforcing features in all directions. FRCs due to their interesting properties are enormously favored by civil and structural engineers. Natural and synthetic fibers can be employed in concretes, shutcretes and mortars. The interface between the added fibers and the cementitious matrix fundamentally influences the properties of the FRCs. Fibers are classified into hydrophobic and hydrophilic. The former fibers have negligible moisture absorbent capacity while exhibiting acceptable mechanical properties. Hydrophobic fibers are incapable of forming adequate adhesion with cementitious matrix. Properties such as low weight, strength parity in wet or dry conditions and inertness in acid or alkaline environments are among the salient properties of polypropylene (PP) fibers. PP as a hydrophobic fiber has gained wide acceptance as concrete reinforcement. The hydrophobicity of fibers, such as PP, has been always been disadvantageous for the use of these fibers in concrete structures. Treatments such as chemical surface modification imparts hydrophilic property to PP fibers. Thus the modified PP fibers can successfully adhere to concrete matrix. In this research melt-spinning technology as the most widely used manufacturing technique for production of the PP fibers was used. Pure and grafted anhydride maleic PP granules were used to produce both hydrophobic and hydrophilic PP fibers. The produced fibers were characterized according to relevant standards prior to be added to concrete samples at identical fiber volume fraction. The results pointed to the positive effect of the induced hydrophilic properties in the fibers as far as the fiber-matrix adhesion was concerned. The ability of the chemically modified fibers to absorb water when wetted with the moisture present in the concrete, greatly improved the adhesion of the added fibers with the concrete matrix. The effect of hydrophilicity of PP fibers on mechanical properties of reinforced concrete was investigated by comparing concrete samples prepared by modified and unmodified fibers. Results showed that in comparison to control concrete sample, addition of modified hydrophilic fibers to concrete enhances compressive, tensile and flexural strength of concrete by 11%, 43% and 75% respectively. It was found that compressive, tensile and flexural strength of concrete samples containing the chemically modified fibers were respectively higher by 5%, 8% and 5% in comparison to the concrete samples containing unmodified hydrophobic fibers. Addition of fibers is more effective in enhancement of flexural strength of resultant concrete. This is due to the fiber bridging phenomena that prevent both crack formation and propagation. Addition of fibers also improves load bearing capacity of the resultant concrete, which in turn leads to enhancement of flexural strength of the concrete. Results also showed that addition of hydrophobic polypropylene fibers leads to 66% increase in the flexural strength of the samples. The increase in flexural strength of the concrete samples containing hydrophilic fibers in comparison to the control sample was found to be 75%.
 

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Aims: Premature ovarian failure is a syndrome causing amenorrhea, infertility, and increases gonadotropin levels before age 40. The use of chemotherapy drugs can be one of the reasons that lead to this disorder. The purpose of this study was to evaluate the presence of germ cells markers in mice model of premature ovarian failure following chemotherapy drugs.
Materials and Methods: In this study, 24 mature female mice were used to create a premature ovarian failure model, different amount of cyclophosphamide and busulfan were applied (experimental groups 1 to 5). Bodyweight change, vaginal smear, morphological alternation of ovarian tissue in both experimental and control (without treatment) groups were evaluated and for the best model, hormonal evaluation (FSH, E2), and expression of germline markers (Oct4, Dazl) were examined.
Findings: Since, in the second group estrus cycle disorder, the significant decrease in weight and ovarian reserve (p˂0.05) were observed, compared to the control group, so this group was chosen as the best model. An increase in FSH level and reduction in estradiol level in the second group, compared with the control group (p˂0.05), confirmed creation of the POF model. Also, genes expression of Oct-4 and Dazl showed an increase (p˂0.05) in the second group compared with the control one.
Conclusion: The presence of germ cells markers in a mouse model of premature ovarian failure following the use of chemotherapy drugs can be a new hope in the treatment of infertility in cancer patients after chemotherapy.
 

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Over the last three decades, there has been a general tendency for changing research methods on soil resource management from conventional and mainly qualitative methods to quantitative ones based on spatial correlation models, which are called Digital Soil Mapping (DSM). The present study was carried out in Shabankareh Plain (15,000 ha) with different physiographic units, in Bushehr Province, southern Iran. The target sites (172 points) were selected for soil sampling at depths of 0-30 cm. Soil texture classes DSM was produced by two methods. The first method was Conventional DSM, in which data of soil particles was obtained from laboratory analysis for each sampling point along with their geographical location. Also, the study area boundary was added to ArcGIS software in UTM format and was analyzed by operating Kriging or IDW estimators. The map produced by this method was a low quality digital map containing extra and scattered texture classes with unrealistically sharp boundaries. The second method used CoKriging of L8 multispectral imagery data (OLI bands) and soil samples analysis was operated. Results showed that using B1 band (0.433-0.453 µm) of Landsat 8 satellite imageries of the study area in April 2020 produced high quality digital maps. In this method, soil textures were the same as the ones in the study area. Salt accumulation and water content of surface soil were possible reasons indicating why satellite imageries in the other periods of year were not suitable for DSM. The highest and the lowest ranges of influence among soil texture parameters were 684 meters and 388 meter for clay and sand particles, respectively.